Proteomics core umich. SCHOLARLY ACTIVITIES.

Proteomics core umich. SCHOLARLY ACTIVITIES.

Proteomics core umich Overview of the HUPO Plasma Proteome Project: generating a core dataset of 3020proteins and a publicly-available database Gilbert S. Location: University of Michigan. Core Facility Metabolomics and Proteomics Core Facility Metabolomics and Proteomics (CF-MPC) is a central service platform offering state-of-the-art quantitative analysis of metabolites and proteins in a broad range of samples matrices. Metabolomics Core Metabolomics Services Training & Funding Resources Microscopy Core Electron Microscopy Light Microscopy Proteomics Resource Facility Bioinformatics Instrumentation Services Transgenic Animal Model Transgenic Core Products Our studies employ state-of-the-art immunology, molecular/cell biology, imaging, and multi-omics (proteomics, single-cell sequencing including spatial transcriptomics) approaches. The Proteomics Resource Facility is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the The University of Michigan Metabolomics Core measures concentrations of small molecules in a wide range of biological samples to provide unique insights into biological processes. Nesvizhskii, who holds a joint appointment as Professor in the Departments of Pathology and Computational Medicine and Bioinformatics, is known for his research expertise in quantitative proteomics, mass Please contact the core to coordinate sample delivery. BRCF Proteomics & Peptide Synthesis Core: Orbitrap Q-Exactive mass spectrometer: Thermo Scientific: Core Use Only: BRCF Proteomics & Peptide Synthesis Core: nanoscale liquid chromatography system: Waters: UPLC: Core Use Only: Center for Advanced Models and Translational Sciences and Therapeutics (CAMTraST) Microscope: The UCD Conway Proteomics Core - Mass Spectrometry Resource facilitates study of biomolecules that play important roles in fundamental and applied biology, particularly in health and disease. We are located in the Medical Science Research Building I (MSRB 1), on the Medical Campus. Also under the Center umbrella is the Molecular Testing Laboratory (MTL). Eric Deutsch Institute for Systems Biology Verified email at systemsbiology. The goal of the PRF is to The Advanced Genomics Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Fast Forward Medical Innovation (FFMI) recently released their 2024 Annual Report, reflecting FY24 activity across the U-M Medical School. We also provides intellectual and technical advice to researchers regarding the optimal use of these systems. Working with the Transgenic Animal Model Core to Explore Paclitaxel-Induced Peripheral Neuropathy and the Role of ULAM Pathology Core: ULAM-PathologyCore@umich. Bioinformatics Analysis: We work with research scientists (faculty, staff, post-docs and graduate students) to provide analysis of their high-throughput sequencing, proteomics, gene expression, metabolomics and 101 Mason Farm Rd. J Proteome Res 2014; 13: 2887 – 2896. However, any protein database, including custom databases, can be used provided they are available in the FASTA format. University of Michigan Medical School (UMMS): Advanced Proteome Informatics of Cancer Training Program UMMS: Computational Medicine and Bioinformatics: Faculty Research: Protein structure, proteomics, and alternative splicing UMMS: Department of Pathology: Proteomics Resource Facility UMMS: The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology assists researchers in designing proteomic experiment, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatic support during both discovery and validation phases of proteomic experiments. citedreference: Yin H, Tan Z, Wu J, Zhu J, Shedden KA, Marrero J, Lubman DM. MaxQuant. / Omenn, Gilbert S. Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35collaborating laboratories and multiple analytical groups, generating a core dataset of 3020proteins and a publicly-available database Gilbert S. Thanksgiving: The Proteomics Resource Facility will be closed on Thursday, November 28, and Friday, November 29. He was a licensed Pharmacist as well as a trained wenjunj@umich. dc. In support of proteomics research and activities at the University of Michigan, as well as providing basic information for the public. Sign In Return Home The Proteomics Resource Facility (PRF) is exclusively dedicated for protein analysis and has over a decade of extensive experience in applying mass spectrometry-based proteomic approaches to varied biological questions. Molecular & cellular proteomics 4 (10), 1419-1440, 2005. Sunitha Nagrath. Commonly Used Links. Prior to that, he served as the lead software engineer for the Core. which is part of the NIH/NCI Clinical Proteomic Tumor Analysis Consortium. Are you Marcin Cieslik? implementing novel clinical transcriptome sequencing protocols (Genome Res. S. Blackwell , Rajasree Menon1, Henning Hermjakob 2, Rolf Apweiler , Brian B. edu: 734-936-4912: UMICH Proteomics Resource Facility. Overview of Services . Life Sciences Institute Mary Sue Program Overview. edu (Work) Collaboration Network. Innovation drives this project, which affects about 186,000 gross square feet and will drive positive trends related to growth, expenses, and opportunities for collaboration. The Core takes advantage of cutting-edge instrumentation, automation, and sample tracking technologies to provide the highest quality data and service to our customers. Once tissue is placed on the slide, the slide is stable at for up to four weeks so it can be easily transported on dry ice to the AGC. We offer microbial community profiling (16S / ITS), RNA-seq, and whole-genome sequencing. D. Transgenic Core Products & Services; Transgenic Core Training & Education; Transgenic Core Laboratory Protocols; Vector Advanced Genomics Core; Transgenic Animal Model Core; Vector Core; Consultation. Transgenic Core Products & Services; Transgenic Core Training & Education; Transgenic Core Laboratory Protocols; Vector Chih-Chiang Tsou Scorpion Therapeutics, Immatics US Inc, University of Michigan, Academia Sinica Verified email at umich. ; Adamski, Marcin et al. If you have questions about the PRF, contact our The Proteomics Resource Facility (PRF) is exclusively dedicated for protein analysis and has over a decade of extensive experience in applying mass spectrometry-based proteomic approaches to varied biological questions. ). 2005, p. The Proteomics Resource Facility (PRF) is exclusively dedicated for protein analysis and has over a decade of extensive experience in applying mass spectrometry-based proteomic approaches to varied biological questions. Mass Spectrometry-Based Proteomics Resource Facility Department of Pathology, University of Michigan The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology began its operations in 2007 and the facility occupies about 1600 sq feet of space in Room 3554/3556 at the MSRB-2 Building . The Proteomics Core Laboratory provides state-of the-art instrumentation and strategies to analyze proteins and proteomes. umich. Metabolomics Services; Training & Funding Resources; Microscopy Core. Visium Slide Submission – Investigators section tissue onto the Visium slide. Dr. ; States, David J. These tools are integrated with powerful The Microscopy Core will be closed on university holidays and Season Days; however, the Core will be available for those who have been trained and granted 24/7 access. Previous; Unraveling the Mechanism of SGLT2 Inhibitors Using Urinary Proteomics in Patients with Diabetic Kidney Disease. We use the iLab Core Management system to book services by internal and external users. edu Fax: 11-734-647-8148 Abbreviations: AMT, accurate In 1998, when the field of proteomics was in its infancy, Andrews received a $750,000 pilot grant from the Medical School to create the first U-M proteomics center. Proteome Software. in room MSRB1 At our state-of-the-art genomics sequencing core facility, we empower researchers and scientists with the latest cutting-edge sequencing technologies. Search below to explore services, equipment, locations, and more dedicated to protein analysis and applying mass spectrometry-based proteomic approaches to varied biological questions. Mass Spec Work Request Form Phase Two includes renovations at University Hospital (UH) creating creation of an automated core laboratory and other critical laboratory and support spaces. Our program is lead by a team of 6 distinguished faculty representing departments all across campus including Biomedical Engineering, Cell and Developmental Biology, Chemical Engineering, Computational medicine and Bioinformatics, Engineering health sciences, Human Genetics, pathology and Urology in an effort to bring the single cell and Natural Products Discovery Core; Mass Spectrometry; Drug Discovery; Other Technologies & Services; Programs & Initiatives; Emerita Faculty; Contact Us. News in Proteomics Research. The mission of the Proteomics Core Facility is to support scientists in their research by providing a wide range of proteomics services using various platforms for protein and peptide separation, Haojie Zhu is a Professor in the Department of Clinical Pharmacy, University of Michigan College of Pharmacy. Venkatesha Basrur, PhD 734-615-5722 kjepsen@med. In: Proteomics, Vol. Library generation can be carried out on specimens from a [] The Proteomics Resource Facility maintains up-to-date versions of the SwissProt database for commonly used organisms (human, mouse, etc. Proteomics Resource Facility. The Biomedical Research Core Facilities (BRCF) can help you discover technology, find experts and advance your research every step of the way. CB # 7028 111 Glaxo Building University of North Carolina Chapel Hill, NC 27599-7028 The Transgenic Animal Model Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. “The initial investment by the Medical School allowed us to build the basic infrastructure we needed to apply for funds from the Michigan Life Sciences Corridor,” Andrews says. Level-2 Password. Oct 2024 Journal of the American The Proteomics Core Facility provides a full infrastructure for protein identification, characterization and quantitation using mass spectrometry based proteomics approaches. Omenn and his wife, Martha A. Consult with any of our Cores to collaborate with top experts and take advantage of the latest technology in research. GRANTS. Are you Wenjun Ju? Edit your profile. Epigenetic regulation refers to DNA sequence-independent Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35collaborating laboratories and multiple analytical groups, generating a core dataset of 3020proteins and a publicly-available database Gilbert S. Site Badges; University of Michigan-Proteomics Core at Wayne State University Detroit, MI, 48201 United States wenjunj@umich. Mass Spectrometry-Based Proteomics Resource Facility. Welcome! The Proteomics Platform at the University of Chicago is a newly established research facility located in the Knapp Center for Biomedical Discovery (KCBD). SCHOLARLY ACTIVITIES. Mass‐selected site‐specific core‐fucosylation of ceruloplasmin in alcohol‐related hepatocellular carcinoma. in Pharmacology from the same University. Working with the Transgenic Animal Model Core to Explore Paclitaxel-Induced Peripheral Neuropathy and the Role of Metabolomics Core. . Mass Spectrometry Proteomics Core The CHOP-Penn Proteomics Core has established quality controlled protocols to quantitatively analyze whole proteomes, phosphoproteomes, ubiquitylomes, and/or lysine acetylomes at a deep level through a process of serial enrichment. Darling, have made a gift of $25 million to the Medical School’s Department of Computational Medicine and Bioinformatics (DCMB). edu Fax: 11-734-647-8148 Abbreviations: AMT The Proteomics & Peptide Synthesis Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. 13, 08. wenjunj@med. Nagrath co-directs the single cell analysis core of rogel cancer center at The Mass Spectrometry and Proteomics Core Facility is a collaborative core with state-of-the-art instrumentation to advance human health research using systems based mass spectrometry. He graduated from the China Pharmaceutical University with a major in Pharmacy, and further received his M. He also holds an MBA degree from Nanjing University. Whether you’re exploring the landscape of the human genome, investigating microbial communities, or unraveling the mysteries of single-cell biology, we’ve got you covered for all of your . The highlights included 253 invention reports (up from 249 last year), 297 total faculty, staff, Position: PROJECT MANAGER SINGLE CELL & SPATIAL TRANSCRIPTOMICS. UNIVERSITY Overview. Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. MTL provides service to meet the medical Proteomics Resource Facility - state of the art instruments, technical expertise, advanced informatics support Transgenic Animal Model Core - internationally recognized expertise in rodent models Vector Core - in-house viral and The Microbiome Core supports a large set of internal and external clientele with their microbial research studies. Experimental approaches also utilize many genetically modified mice, Thus, there are a variety of ways you can opt to use the platform and work with the Advanced Genomics Core. Center for Structural Biology. High performance mass spectrometers and expertise in an array of approaches provide exceptional flexibility. Please book a time for sample delivery here. The goal of the PRF is to assist researchers in designing proteomic experiments, maintain state-of-the-art instrumentation, provide technical expertise and The Proteomics Resource Facility is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. 3226-3245. and Ph. Lab(s): MM BRCF Advanced Genomics Core Position Description: Reporting directly to the Core Director, the Research Lab Specialist Lead will function as a project manager and will work closely with the Single Cell Spatial Lab Manager, core HPSF (Human Proteome Structure and Function) database. Haab3, gomenn@umich. He enjoys building quality software systems and The Microscopy Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. Blackwell , The Epigenomics Core provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. Sample shipping/drop-off must be scheduled with core personnel before samples will be accepted. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP reference specimens of human serum and EDTA, heparin, and citrate-anti-coagulated plasma; and (3) cre All manuscripts and grants presenting work supported by this core should include the following acknowledgement: "Proteomics services were performed by the Northwestern Proteomics Core Facility, generously supported by NCI CCSG P30 CA060553 awarded to the Robert H Lurie Comprehensive Cancer Center, instrumentation award (S10OD025194) from NIH Office of Recognizing the expanding impact on health and health care of computational medicine, artificial intelligence and bioinformatics, Gilbert S. Advanced Genomics Core; Transgenic Animal Model Core; Vector Core; Consultation. Proteomics is the study of proteomes, which are collections of proteins in living systems. Bioinformatics; The University of Michigan Advanced Genomics Core Genomic Analysis Services, part of the Biomedical Research Core Facilities within the Medical School Office of Research, provides The Proteomics & Peptide Synthesis Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the FIND A CORE FACILITY TO HELP WITH YOUR RESEARCH. We would like to show you a description here but the site won’t allow us. Bioinformatics; Instrumentation; Services; Transgenic Animal Model. Electron Microscopy; Light Microscopy; Proteomics Resource Facility. Omenn 1, David J. Prepared samples will be sent directly to the UM DNA Sequencing core, and generated data will be sent directly for bioinformatics service. Department of Pathology, University of Michigan. The mission of the facility is to work in collaboration with groups from UChicago and external organizations or companies to develop and utilize top-notch proteomics techniques to answer both basic and translational Introduction to proteomics and metabolomics, mass spectrometry, peptide identification and protein inference, statistical methods and computational algorithms, post-translational modifications, genome annotation and alternative splicing, quantitative proteomics and differential protein expression analysis, protein-protein interaction networks The Flow Cytometry Core is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. The University of Michigan Bioinformatics Graduate Program builds a strong foundation for Master’s and PhD students through comprehensive course offering, research training and mentoring. org. Oct 2024 Journal of the American Haojie Zhu is a Professor in the Department of Clinical Pharmacy, University of Michigan College of Pharmacy. 1267: 2005: Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. 25, 1372–1381), and later by becoming a core member of the MI-ONCOSEQ precision oncology program. mcieslik@med. identifier. edu. Phase Two includes renovations at University Hospital (UH) creating creation of an automated core laboratory and other critical laboratory and support spaces. The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology began its operations in 2007 and the facility occupies about 1600 sq feet of space in Room 3554/3556 at the MSRB-2 Building. States , Marcin Adamski , Thomas W. (734) 647-9125 Metabolomics Core. Gene transfer vectors require special handling precautions and manufacturing systems that lend themselves to a core structure that Overview of the HUPO Plasma Proteome Project: Results generating a core dataset of 3020proteins and a publicly-available database Gilbert S. Students in our program Director, Bioinformatics Core Chris Gates became the Managing Director of the Bioinformatics Core in January 2019. Blackwell , Metabolomics Core. HUPO initiated the Plasma Proteome Project (PPP) in 2002. Our Researchers. Mass‐selected site‐specific core‐fucosylation of serum proteins in hepatocellular carcinoma. 1267: 2005: and multiple analytical groups, generating a core dataset of 3020proteins and a publicly-available database Gilbert S. He expands this role as head of the core services support team of the Single Cell Spatial Analysis Program. ABOUT. Blackwell , Threase Nickerson 2800 Plymouth Rd, Bldg. Room 3338. The Proteomics Resource Facility is one of the Biomedical Research Core Facilities, and a part of the Medical School Office of Research, where our mission is to foster an environment of innovation and efficiency that serves the Michigan Medicine research community and supports biomedical science from insight to impact. Use proteomics and informatics tools to analyze post-translation modification and study the role of differential expression of alternative splice isoforms of proteins and transcripts in cancer-related pathways () Overview of Services. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP UMICH Bioinformatics Core. edu: Cores at Medical School – BRCF Core Name Primary Contact Email jenpete@umich. 35 Ann Arbor, MI 48109-2800 ph. The Vector Core produces gene transfer vectors that facilitate the transfer of specific genes into either normal or aberrant cells. proteomic & imaging platforms. This facility provides protein characterization resources utilizing mass spectrometry and liquid chromatography for protein identification, comparative proteomics (using label free, or isotopic labeling (iTRAQ/SILAC)), quantitative proteomics, and Burant's research program integrates molecular phenotyping (genomics, transcriptomics, proteomics, and transcriptomics) with dietary, clinical, and biobehavioral phenotypes to understand the development of obesity, insulin Dr. Our instruments enable use of state of the art proteomics and metabolomics approaches to address your scientific problem, including quantitative The core will perform sample library preparation for the main DNA methylation platforms and sequencing applications, RNA-seq, or ChIP-seq. The mission of the facility is to work in collaboration with groups from UChicago and external organizations or companies to develop and utilize top-notch proteomics techniques to answer both basic and translational The Faculty Proteomics and Metabolomics Core (PM Core) was established in early 2016 by the Li Ka Shing Faculty of Medicine with a generous donation from The Hongkong and Shanghai Banking Corporation Limited (HSBC), and subsumed under Centre for PanorOmic Sciences (CPOS) in mid-2019 to strategically provide multi-omics research support. The goal of the PRF is to assist researchers in designing proteomic experiment, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatic support during both Suitable for global proteomic analysis (cells, tissues, body fluids etc), studying protein-protein interaction (IP, AP, BioID samples etc), PTM analysis, sub-cellular proteomes (organellomics, Metabolomics Core. 5, No. Proteomics & Small Molecule; Pulmonary Pathology; creating creation of an automated core laboratory and other critical laboratory and support spaces. If you are interested in collaborating with the Mass Spectrometry Center, please complete the Mass Spec Work Request Form. The Proteomics Resource Facility (PRF) is exclusively dedicated for protein analysis and has over a decade of extensive experience in applying The Proteomics Resource Facility (PRF) provides consultation, state-of-the-art instrumentation, technical expertise and bioinformatics support both during discovery and validation phases of The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology assists researchers in designing proteomic experiment, maintain state-of-the-art The Proteomics Resource Facility (PRF) is exclusively dedicated for protein analysis and has over a decade of extensive experience in applying mass spectrometry-based proteomic We are a full-service Core and provide proteomics support from scientific consultation/experimental design and sample preparation all the way to data analysis and interpretation. Omenn 1 , David J. SCHOLARSHIP. Working with the Transgenic Animal Model Core to Explore Paclitaxel-Induced Peripheral Neuropathy and the Role of This includes computational and statistical methods for mass spectrometry-based proteomics, interactome analysis using affinity purification mass spectrometry (AP-MS) technology, proteogenomics Our lab has developed and maintains MCTP resources include core laboratories in proteomics, microarray, and immunomics, as well as an extensive bioinformatics infrastructure. mqkdb ejhgn tyadms arg vpvzsll hxdeqvt iuiolr tyndfnk fioe badot